Amylase or alpha-amylase (diastasis) is called the enzyme of the digestive system, which produces pancreas. It intensively digested food, cleaves carbohydrates, helps the normal absorption of glucose. In addition to the diastase, the pancreas can produce another enzyme - lipase responsible for fats cleavage.
Amylaza actively participates in the digestive process
Norms of amylase in human blood
The amylase enzyme is produced to a greater extent in the pancreas, and in smaller-salivary glands. With the normal operation of the digestive system of amylase, the complex carbohydrates in glucose turns. Next, glucose enters the intestine, where it is absorbed into the blood, and then excreted by the kidneys outside.
In the study of the blood of amylase, this is the main screening analysis of pancreatitis, according to its indicators, the activity of the digestive system is watched. Alpha-amylase is an enzyme of the pancreas and an indicator of the total amount of amylase in the body. One of the components of diastase is a pancreatic amylase that produces pancreas juice and is fully responsible for the operation of the pancreas. Amylaza General and amylase pancreatic have their own values \u200b\u200bof the norm. So, the norm in the blood of a person should be:
- from birth to 24 months. rate - 5 - 70 units / liter;
- from 24 months. up to 75 years norm - 15 - 130 units / liter;
- in the older period, the norm is up to 160 units / liter.
The rate of amylase in the blood is established depending on age indicators
Indicators of Pancreatic amylase are somewhat different from the values \u200b\u200bof the amylase common. In healthy newborn amylase, pancreatic in the blood should be not more than 8 units / l, and kids from 12 months and in adults - up to 50 units. / L.
Laboratory diagnostics of amylase with pancreatitis
The level of amylase in the blood is possible to determine by passing the analysis of biochemistry from Vienna. The analysis is better to hand over the hungry stomach and in the first half of the day, then the result will be more correct. Also on the eve of the study, it is advisable not to take bloodboring preparations (aspirin, kuranyl), eliminate the saham-containing products, do not use fatty and acute food, as well as alcohol. At least a few hours before the procedure, it is worth refraining from smoking, because nicotine affects the change in blood composition and leads to the formation of thrombov.
The procedure for the collection of blood on amylase takes only a few minutes and is carried out by taking biological material (5-10 ml) from peripheral veins, using a disposable sterile medical instrument. The appointment for blood test on the necessary indicators is written out by the doctor to diagnose a more accurate cause of certain complaints (for example, acute abdominal pain). Conducts the procedure for the collection of blood nurse procedural cabinet clinics at the place of residence. The result should not make yourself wait - in an emergency, the indicators can be found for half an hour.
Blood fence for tests is made from peripheral veins
Deviations from the norm - how dangerous
Not always, but in most cases, the amylase pancreatic can be increased in inflammatory actions in the pancreas, when pancreatitis is possible. It is a pathology that occurs most often from the rejunctional use of alcohol and improper nutrition when the gallbladder is blocked with the formation of stones.
Alfa-amylase is an enzyme that contributes to the splitting of proteins in the organism of people. The production of this substance is responsible. Possible disorders of the digestive system may occur in a situation when the patient in the patient alpha-amylase is increased.
Self-medication in such situations is strictly prohibited, since such actions may cause significant violations in the work of the body.
Pancreas produces alpha amylase.
The main biological function of alpha-amylase is the splitting of certain carbon fibers to less complex compounds like starch and glycogen.
Such processes contribute to improving the efficiency and assimilation of a significant amount of nutrients.
The functionality of the pancreas allows mixed secretion, due to which the alpha-amylase comes not only in the digestive, but also in the circulatory system. There are two main varieties of this enzyme:
- The amylase of the saliva is produced in small volumes directly in the process of operation of the salivary glands. At the same time, the process of primary digestion of food is launched in the oral cavity, and the secretion of gastric juice is stimulated.
- Pancreatic amylase is a product of the pancreas work, contributes to the digestion process, breaks down certain components of the food received into a few simple.
The amount of enzyme in the body makes it possible to determine numerous disorders of the digestive system that do not have any pronounced symptoms.
Normal alpha-amylase
Captopril is undesirable to use before analysis.
The level of pancreatic amylase in the normal state without any diagnosed problems with the pancreas will be close to zero.
The indicator below 50 units can also be regarded as normal, is not the cause for concern. In order for the results of the tests to be more accurate, it is better before the procedures do not eat food.
The secretion process is initiated immediately after the food is placed in the oral cavity. It is for this reason that even a small amount of food may cause inaccurate results of analyzes. The attending physician is advisable to warn before conducting analyzes if the patient accepted such drugs:
- Ibuprofen;
- Oral contraceptives;
- Various diuretic products.
These have a certain impact on the gland, contribute to the intensification of secretion. If real problems are absent, the level of amylase will be normalized for one month.
How to treat pancreatitis - in the thematic video:
Causes of increasing the amount of enzyme
The reasons for increasing alpha-amylase can be a different, manifest itself constantly or periodically. Continuous changes in the body are not yet evidence of various diseases, disorders and deviations.
In general, the patient's well-being can also be degraded. Determine the presence of any pathologies will be able to systematically increase the amount of enzyme in the blood. Also experienced doctors recommend paying attention to the following symptoms:
- , in the right side after meals;
- Frequent diarrhea, in most cases at night;
- Caught fatigue.
The reason for increasing the amount of the enzyme may be intensive work of the pancreas itself.
It is necessary to name a list of diseases that contribute to such a violation:
- Pancreatitis violates the pancreas. In such situations, you can observe a negative impact on the hardware produced by it. If you do not conduct therapy in a timely manner, pancreatic drugs can develop, implying pancreas ,. In the adult population, such pathology may be diagnosed in most situations due to alcohol abuse. Such violations may cause patient death;
- Systematically emerging violations of the normal operation of the pancreas can help increase the amount of alpha-amylase;
- Oncological processes developing in the pancreas are the reason for increasing the amount of enzyme in the body of about 4 times;
- Formation of concrections in;
- In diabetes, there is a general metabolism failure that is accompanied by irrational enzyme production;
- Parotitis worsens the general condition of patients. In salivary glands occur inflammatory processes. After treatment, the production of alpha-amylase is normalized;
- General renal failure is a disorder in which the amylase can delay in the circulatory system.
These are the main causes of disorder.
What could mean an increase in alpha-amylase?
Analyzes will help to establish the level of the enzyme in the body.
Additional examinations The attending physician will be prescribed even in a situation where the amount of enzyme in the blood rises slightly.
In some situations, the increase can be purely random, be caused by an insignificant deterioration in the quality of the work of the immune system. The diseases may be discussed when the alpha-amylase level increases in about 2 or more times.
In such situations, patients may experience intensive pain in the stomach, lose appetite. At the same time, it is desirable to deliver a patient in a timely manner in a hospital in a timely manner, because, as mentioned earlier, such a state can cause death.
Often the intensity of pain increases so much that the patient can not move. It is performed individually using individually selected techniques. For a long time, oncological processes may not give any information about themselves. The general condition is only slightly deteriorating, the weakness of drowsiness appears.
Treatment of tumor processes is carried out only individually specially selected methods involving the operational intervention of doctors, as well as the appointment of certain potent drugs.
Reducing the number of enzyme
Bed regime - will help reduce the level of amylase.
If, according to the results of the analyzes, it is possible to determine the increase in the level of alpha-amylase in the circulatory system, first will have to determine the cause of this deviation.
Only after that you can try to prescribe therapeutic procedures and suitable drugs. The general principle of working to reduce the level of amylase implies such actions:
- If there is an inflammatory process, it is desirable to observe a strict bed mode, reduce the total number of physical and intellectual loads on the body;
- For the period of treatment, it is desirable to increase sleep duration up to 8.5-10 hours;
- It is necessary to breathe fresh air as much as possible. This will contribute to the stabilization of the metabolic process, to have a positive impact on regulating the number of enzymes, among which pancreatic amylase includes;
- It is also necessary to normalize the diet in the treatment of disorder. It is advisable to limit the use of alcohol-containing liquids, coffee, chocolate, as well as strong tea, canned food, dry food, as well as food containing a large amount of fat. It is necessary to distribute the diet for a certain amount per day.
The elevated level of alpha-amylase is a sign indicating the need to pay attention to its health. In the initial stages it is desirable to conduct an appropriate examination, contacting a qualified health worker.
The doctor develops a plan for therapeutic procedures, which must be accurately followed. If you try to reduce the level of amylase in the blood yourself, you can create additional problems for which the permission of which will still have to access the doctor.
Tell your friends! Tell us about this article to your friends in your favorite social network with the help of social buttons. Thank you!
Telegram
Together with this article read:
In the digestive process, many microelements and organic substances are involved, with the help of which starch, carbohydrates, fats, etc. are splitted. One of them is considered amylase. The enzyme actively splits carbohydrates, starch to simpler compounds. The amylase is formed in the glands: dairy (in pregnant women), salivary, pancreas, as well as in kidneys and liver. Displays through the urinary system. Amylase is divided into three types: alpha, beta, gamma. The reduced or high concentration of alpha amylase, as well as other groups, can adversely affect human health. If the amylase in the blood is strongly improved, you need to take action, and treat an atypical deviation.
If alpha amylase is too raised, it is very possible to develop in the body of a pathological process. Timely diagnosis will allow to assign proper treatment. When studying the concentration of the enzyme in the blood, special attention is paid to alpha amylase, since these organic substances directly affect the operation of the digestive system. Normal state for the body is considered if the level of alpha amylase is exceeded by several units. Treatment in this case will not be required, since such an anomaly is temporary.
Causes of the presence of alpha enzyme in the blood - possible diseases or injuries of the pancreas, organs of the digestive system. At the same time, the work of the damaged body is violated. The blood test for the content of alpha amylase is prescribed by a specialist to determine pathologies associated with salivary, pancreas, stomach. The reduced concentration of amylase may be a consequence of diseases of salivary glands, chronic pancreatitis and other diseases.
Causes of painful processes in the digestive system in adults or a child - a possible increase in amylase level several times. In particular, the symptoms are as follows:
- pain in the right side of the abdomen, often after meals;
- weakness, malaise;
- the appearance of diarrhea.
The main reasons for the diagnosis of amylase in the blood are pronounced pain, enhanced pancreatic functioning. It actively produces an organic matter, which immediately enters the blood system. This is due to the increased production of pancreatic juice, a special liquid medium, which is produced by the pancreas in the duodenum. Other reasons when amylase is raised - difficulty advanced protocates, current inflammations in the pancreas or in related organs. All this may testify in favor of necrosis or injuries of various nature.
High amylase associated diseases
What you need to do if certain doubts about the normal level of amylase are present. First of all, to hand over a biochemical blood test. It is appointed by a profile specialist for the presence of various pathologies in the body. Venous blood is taken for research. The test must be held in the morning, on an empty stomach. For adult men and women, the usual level ranges between the marks 25-125d / l. People have over 70 years old, the normal figure is 20-10-10d / l. For kids up to two years, this value should be around 5-65 wedd / l. Acute abdomen pains can cause a high level of enzyme. Therefore, together with other studies, the doctor is obliged to appoint a biochemical blood test and further, choose a comprehensive treatment.
Increased amylase can be a consequence of severe ailments.
- Parotitis. Deals are more famous as a pig. With such a disease, salivary glands are inflated in the secretion of organic matter.
- Diabetes. Complicated pathology, which is based on a violation of metabolism, as a result of which the level of amylase is inconsistent. The content of the enzyme in the blood increases.
- New formation in the pancreas. The reason for increasing the amylase is considered primarily a cancer tumor. In this case, the density of the organic matter will rise several times.
- Renal failure. The diseases associated with the kidneys, destruct the correct operation of the allocation functions, which leads to the accumulation of the enzyme in the body and in particular in the blood.
- Peritonitis. Heavy pathology, which is based on inflammation of the peritoneum. Failures in the functioning of the pancreas lead to the activity of its cells and further, an increased enzyme concentration.
- Cholelithiasis.
When the amylase is increased, perhaps the development of chronic pancreatitis. Pancreas dysfunction provokes the growth of organic matter in the blood to five times.
What else affects the level of enzyme
However, this is not a complete list of possible reasons, which is why the amylase increases. The level of the enzyme is high due to other signs, for example:
- abortion;
- abuse of alcohol drinks;
- herpes virus;
- ectopic pregnancy;
- complications after surgery;
- obstruction of the intestinal tract;
- macroamilaisemia.
There is also a sense to add: violation of the proper nutrition mode, the reception of medicines (contraceptives, diurendic, contraceptive, caption, ibuprofen, cedema, furosemide), genetic diseases. All this can increase amylase in the blood. Even after severe stress, the concentration of the enzyme increases.
What to do and take if the fact of increased amylase appeared when diagnosed? In this case, some blood studies are not enough. To assign comprehensive therapy, additional analyzes will be required, and only on the basis of all data the doctor will be able to establish the cause of the anomalies. If the pathology of acute form has been identified, immediate treatment is required, and in frequent cases it will flow within the hospital walls.
The basis of recovery is considered the correct diet, since alpha amylase is a digestive enzyme. The patient will be obliged to abandon the usual lifestyle if it was wrong in terms of the power mode, and proceed to the use of recommended products. This rule primarily concerns those patients who have diagnosed hazardous diseases: pancreatitis, diabetes and the like.
To reduce the load on the gastrointestinal tract, the patient will have to refrain from large portions.
He should eat in small quantities - four, five times a day. A taboo will be put on alcoholic beverages, coffee, strong tea. Doctors, with a high level of enzyme recommended separate meals to improve well-being. Also necessary to abandon the drift, oily, smoked, fried food, marinades, garlic, bow, radish.
Prefer a paired food prepared in a double boiler. It is not recommended to smoke during the appointment of therapy. The level of proteins should be monitored in food consumed and abandon meals with a large content of fiber. It provokes an increase in organic matter. Useful are considered: vegetable soups, fish and meat of non-fat varieties, porridges on the groats, natural juices, nice cottage cheese. Structured rules must be observed after curing the underlying disease, the normalization of the amylase level. In this case, the probability of repeated diseases and an increase in the concentration of the enzyme will fall at times.
Human body Contains in a huge amount of various useful substances and trace elements. At the same time, they all play a very large and important role.
If any problems arise, then this is evidenced by an increased or reduced level of blood enzymes. Neglect of these signals may lead to the development of serious diseases.
The role of amylase in the human body
Amylase is a very important digestive enzyme, with which carbohydrates are split.
In addition, it is involved in the process of digestion, so it is necessary that its level of content in the human body is within the normal range.
Produces amylase Pancreas When a person is used by starch products, such as rice, potatoes and others, liver, intestines and dairy glands during breastfeeding. In the human body, this enzyme is several types. This is alpha, beta and gamma.
Using urine and blood studies, an increase in amylase is determined. So that the results were reliable, It is necessary to take simultaneous tests.
Blood is taken venous in the morning and preferably an empty stomach. If the case is complex, the studies are carried out immediately, as the patient asked for help.
At the same time drawn attention to several factors: at what time of day the tests are taken, and how many foods received a person.
After the food entered the human mouth, immediately the digestive process beginsin which saliva is involved and the amylase enzyme present in it.
Its normal content is the amount of 25 to 100 per liter of blood plasma.
There is still pancreatic amylase, the content of which one liter of plasma should not exceed 50 units.
This indicator is the maximum And the level of the enzyme is less, the better for the human body.
What reasons affect the increase?
If there is a suspicion of such ailments as a cyst, a malignant and benign tumor, with pancreatitis and complaints of the pancreas.
There are many factors capable of providing an increase in the level of enzyme. Among the most common the reasons are allocated as the following:
- Acute pancreatitis. The consequence of attacks is an increase in amylase, which sometimes reaches significant deviations;
- Diabetes. In most cases, analyzes are determined by increased alpha-amylase;
- For diseases of the gallbladder and biliary tract. In most cases, the elevated level of the enzyme is observed in harticism;
- With mechanical impact, which can be a blow to the abdomen before starting research. Most often, the result of the tests will be distorted;
- The high level of the enzyme is noted if urolithiasis and renal failure are present;
- In some cases, active generation of amylase occurs if there are salivary glasses;
- Acute or chronic form of hepatitis;
- If the pancreas is removed;
- With fibergation.
Also, the increase in amylase is celebrated in people who abuse alcohol, after staying in a shock, after a person experienced strong stress.
Some medical preparations have a negative impact on the human body:
- Ibuprofen;
- Furosemide;
- Captopril;
- Cytemed;
- Diolets and contraceptives.
Treatment of elevated blood levels
The human body independently produces amylase.
For stimulating This process exists certain methods, however, the abuse of them is able to negatively affect the patient's health.
In order for the treatment to be gentle and efficient, the selection of drugs is engaged only by an experienced specialist.
It is possible to treat an increased level of amylase in the blood only after a complete examination is performed and the exact diagnosis is determined.
The whole process will be aimed at eliminating the cause, caused this phenomenon. It should be noted that an individual approach is carried out to each patient, where the stage of the disease and the overall health of health play a very large role.
With proper treatment of the disease provoked an increase in the level of amylase, all indicators are normalized.
Diet at elevated enzyme
For diseases such as pancreatitis, diabetes and other causes of amylase, the diet is recommended.
At the same time, special attention is paid to the amount of protein consumption and reduction or complete exception of carbohydrates and fats. Need to abandon fried dishesIt is undesirable to eat products that contain a large amount of fiber.
Each eating follows in smaller quantities, but it is much more likely to do, it is preferably at least six times a day. Vegetable soups, nice cottage cheese, juices of various fruits and berries, porridge, meat and fish are better than non-fat varieties.
It is important to know that any error during a diet can immediately have a negative impact on the pancreas. From proper nutrition during the treatment period, it depends how long it will last.
If the alpha-amylase is lowered in the blood, the reasons must be sought in the digestive system. You should know that at night this enzyme is produced in minimal quantities. The snacks at night can lead not only to obesity, but also to disorders.
As for the tests, two types of enzyme are detected in the blood:
- S-type - elements that are produced precisely by salivary glands; It must be said that it is 60% of the total;
- R-type - all that is produced only by the pancreas.
Professionals argue that it is important for research to determine not only the total amount of amylase, but also accurate numbers from various organs.
Biological material is rented on the following algorithm:
- Blood samples must be provided only in the morning, necessarily an empty stomach.
- In the case when there are suspicions of pancreatitis, the liquid is taken at any time of the day. Doctors can not afford to leave the patient in serious condition.
- There is one nuance. The last meal must be carried out up to 12 hours before testing. No one alcohol or fat.
- After the procedure was carried out, the blood immediately surrendered to the laboratory. The maximum storage time should not exceed one hour.
- It happens so that it is simply no possibility to conduct a study by this minute. For this, the liquid is frozen.
Norms and deviations
What the situation says when amylase is raised:
- Suspicions of acute pancreatitis. During an attack, the amount of enzyme reaches maximum values \u200b\u200bin the human body.
- Chronic diseases.
- The presence of diabetes. In this case, the overall level is increased, but slightly.
- Suspicions of appendicitis or peritonitis.
- Possible neoplasms or tumors.
- If we talk about women, then the level increase means an ectopic pregnancy.
- Various kinds of poisoning.
- disability of the pancreas;
- various kinds of necrotic changes in organs;
- oncology of liver, stomach or intestines;
- hepatitis;
- toxicosis in pregnant women.
You should know that the accuracy of research should be maximal. On analyzes may even affect the adoption of some drugs:
- oral contraceptive means;
- anesthetics drugs of narcotic type;
- diuretic agents;
- preparations that contain adrenal hormones in the composition.